Mitochondrial DNA Mutations in Respiratory Complex-I in Never-Smoker Lung Cancer Patients Contribute to Lung Cancer Progression and associated with EGFR gene mutation

Mitochondrial DNA (mtDNA) mutations were reported in different cancers. However, the nature and role of mtDNA mutation in never-smoker lung cancer patients including patients with EGFR and KRAS gene mutation are unknown. In the present study, we sequenced entire mitochondrial genome (16.5 kb) in mat...

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Detalhes bibliográficos
Main Authors: Dasgupta, Santanu, Soudry, Ethan, Mukhopadhyay, Nitai, Shao, Chunbo, Yee, John, Lam, Stephan, Lam, Wan, Zhang, Wei, Gazdar, Adi F, Fisher, Paul B, Sidransky, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256258/
https://ncbi.nlm.nih.gov/pubmed/21830212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22980
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