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Curing of Plasmid pXO1 from Bacillus anthracis Using Plasmid Incompatibility

The large plasmid pXO1 encoding the anthrax toxin is important for the virulence of Bacillus anthracis. It is essential to cure pXO1 from B. anthracis to evaluate its role in the pathogenesis of anthrax infection. Because conventional methods for curing plasmids (e.g., curing agents or growth at ele...

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Main Authors: Liu, Xiankai, Wang, Dongshu, Wang, Huagui, Feng, Erling, Zhu, Li, Wang, Hengliang
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256208/
https://ncbi.nlm.nih.gov/pubmed/22253811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029875
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