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Identification of the pXO1 plasmid in attenuated Bacillus anthracis vaccine strains

Anthrax toxins and capsule are the major virulence factors of Bacillus anthracis. They are encoded by genes located on the plasmids pXO1 and pXO2, respectively. The vaccine strain Pasteur II was produced from high temperature subcultures of B. anthracis, which resulted in virulence attenuation throu...

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Detalhes bibliográficos
Publicado no:Virulence
Main Authors: Liang, Xudong, Zhang, Huijuan, Zhang, Enmin, Wei, Jianchun, Li, Wei, Wang, Bingxiang, Dong, Shulin, Zhu, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026784/
https://ncbi.nlm.nih.gov/pubmed/27029580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2016.1164366
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