載入...

Activation of Benznidazole by Trypanosomal Type I Nitroreductases Results in Glyoxal Formation

Benznidazole, a 2-nitroimidazole, is the front-line treatment used against American trypanosomiasis, a parasitic infection caused by Trypanosoma cruzi. Despite nearly 40 years of use, the trypanocidal activity of this prodrug is not fully understood. It has been proposed that benznidazole activation...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Hall, Belinda S., Wilkinson, Shane R.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2012
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256028/
https://ncbi.nlm.nih.gov/pubmed/22037852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05135-11
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!