Chargement en cours...
Activation of Benznidazole by Trypanosomal Type I Nitroreductases Results in Glyoxal Formation
Benznidazole, a 2-nitroimidazole, is the front-line treatment used against American trypanosomiasis, a parasitic infection caused by Trypanosoma cruzi. Despite nearly 40 years of use, the trypanocidal activity of this prodrug is not fully understood. It has been proposed that benznidazole activation...
Enregistré dans:
| Auteurs principaux: | , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2012
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3256028/ https://ncbi.nlm.nih.gov/pubmed/22037852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05135-11 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|