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Downregulation of Mitogen-Activated Protein Kinase 1 of Leishmania donovani Field Isolates Is Associated with Antimony Resistance

Emergence of resistance to pentavalent antimonials has become a severe obstacle in the treatment of visceral leishmaniasis (VL) on the Indian subcontinent. The mechanisms operating in laboratory-generated strains are somewhat known, but the determinants of clinical antimony resistance are not well u...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Ashutosh, Garg, Mansi, Sundar, Shyam, Duncan, Robert, Nakhasi, Hira L., Goyal, Neena
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256019/
https://ncbi.nlm.nih.gov/pubmed/22064540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00736-11
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