Generation of HIV Latency in Humanized BLT Mice

Here we demonstrate that a combination of tenofovir, emtricitabine, and raltegravir effectively suppresses peripheral and systemic HIV replication in humanized BLT mice. We also demonstrate that antiretroviral therapy (ART)-treated humanized BLT mice harbor latently infected resting human CD4(+) T c...

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Main Authors: Denton, Paul W., Olesen, Rikke, Choudhary, Shailesh K., Archin, Nancy M., Wahl, Angela, Swanson, Michael D., Chateau, Morgan, Nochi, Tomonori, Krisko, John F., Spagnuolo, Rae Ann, Margolis, David M., Garcia, J. Victor
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255928/
https://ncbi.nlm.nih.gov/pubmed/22013053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06120-11
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