Herpes Simplex Virus Requires Poly(ADP-Ribose) Polymerase Activity for Efficient Replication and Induces Extracellular Signal-Related Kinase-Dependent Phosphorylation and ICP0-Dependent Nuclear Localization of Tankyrase 1

Tankyrase 1 is a poly(ADP-ribose) polymerase (PARP) which localizes to multiple subcellular sites, including telomeres and mitotic centrosomes. Poly(ADP-ribosyl)ation of the nuclear mitotic apparatus (NuMA) protein by tankyrase 1 during mitosis is essential for sister telomere resolution and mitotic...

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Detalhes bibliográficos
Main Authors: Li, Zhuan, Yamauchi, Yohei, Kamakura, Maki, Murayama, Tsugiya, Goshima, Fumi, Kimura, Hiroshi, Nishiyama, Yukihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255871/
https://ncbi.nlm.nih.gov/pubmed/22013039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05897-11
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