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The Cellular Chaperone Hsc70 Is Specifically Recruited to Reovirus Viral Factories Independently of Its Chaperone Function

Mammalian orthoreoviruses replicate and assemble in the cytosol of infected cells. A viral nonstructural protein, μNS, forms large inclusion-like structures called viral factories (VFs) in which assembling viral particles can be identified. Here we examined the localization of the cellular chaperone...

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Détails bibliographiques
Auteurs principaux: Kaufer, Susanne, Coffey, Caroline M., Parker, John S. L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255859/
https://ncbi.nlm.nih.gov/pubmed/22090113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02662-10
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