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Uncoupling cis-Acting RNA Elements from Coding Sequences Revealed a Requirement of the N-Terminal Region of Dengue Virus Capsid Protein in Virus Particle Formation

Little is known about the mechanism of flavivirus genome encapsidation. Here, functional elements of the dengue virus (DENV) capsid (C) protein were investigated. Study of the N-terminal region of DENV C has been limited by the presence of overlapping cis-acting RNA elements within the protein-codin...

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Detalhes bibliográficos
Main Authors: Samsa, Marcelo M., Mondotte, Juan A., Caramelo, Julio J., Gamarnik, Andrea V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255831/
https://ncbi.nlm.nih.gov/pubmed/22072762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05431-11
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