Identification of a Src Tyrosine Kinase/SIAH2 E3 Ubiquitin Ligase Pathway That Regulates C/EBPδ Expression and Contributes to Transformation of Breast Tumor Cells

The transcription factor CCAAT/enhancer-binding protein delta (C/EBPδ, CEBPD) is a tumor suppressor that is downregulated during breast cancer progression but may also promote metastasis. Here, we have investigated the mechanism(s) regulating C/EBPδ expression and its role in human breast cancer cel...

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Bibliographic Details
Main Authors: Sarkar, Tapasree Roy, Sharan, Shikha, Wang, Jun, Pawar, Snehalata A., Cantwell, Carrie A., Johnson, Peter F., Morrison, Deborah K., Wang, Ju-Ming, Sterneck, Esta
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255785/
https://ncbi.nlm.nih.gov/pubmed/22037769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05790-11
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