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Integration of Regulatory Networks by NKX3-1 Promotes Androgen-Dependent Prostate Cancer Survival

The NKX3-1 gene is a homeobox gene required for prostate tumor progression, but how it functions is unclear. Here, using chromatin immunoprecipitation coupled to massively parallel sequencing (ChIP-seq) we showed that NKX3-1 colocalizes with the androgen receptor (AR) across the prostate cancer geno...

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Main Authors: Tan, Peck Yean, Chang, Cheng Wei, Chng, Kern Rei, Wansa, K. D. Senali Abayratna, Sung, Wing-Kin, Cheung, Edwin
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255774/
https://ncbi.nlm.nih.gov/pubmed/22083957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05958-11
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