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Localization of HET-S to the Cell Periphery, Not to [Het-s] Aggregates, Is Associated with [Het-s]–HET-S Toxicity

Prion diseases are associated with accumulation of the amyloid form of the prion protein, but the mechanisms of toxicity are unknown. Amyloid toxicity is also associated with fungal prions. In Podospora anserina, the simultaneous presence of [Het-s] prion and its allelic protein HET-S causes cell de...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mathur, Vidhu, Seuring, Carolin, Riek, Roland, Saupe, Sven J., Liebman, Susan W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255711/
https://ncbi.nlm.nih.gov/pubmed/22037764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06125-11
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