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A Protective Epitope in Type III Effector YopE Is a Major CD8 T Cell Antigen during Primary Infection with Yersinia pseudotuberculosis

Virulence in human-pathogenic Yersinia species is associated with a plasmid-encoded type III secretion system that translocates a set of Yop effector proteins into host cells. One effector, YopE, functions as a Rho GTPase-activating protein (GAP). In addition to acting as a virulence factor, YopE ca...

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Hlavní autoři: Zhang, Yue, Mena, Patricio, Romanov, Galina, Lin, Jr-Shiuan, Smiley, Stephen T., Bliska, James B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255672/
https://ncbi.nlm.nih.gov/pubmed/22064714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05971-11
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