Disruption of the Phospholipase D Gene Attenuates the Virulence of Aspergillus fumigatus

Aspergillus fumigatus is the most prevalent airborne fungal pathogen that induces serious infections in immunocompromised patients. Phospholipases are key enzymes in pathogenic fungi that cleave host phospholipids, resulting in membrane destabilization and host cell penetration. However, knowledge o...

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Bibliographic Details
Main Authors: Li, Xianping, Gao, Meihua, Han, Xuelin, Tao, Sha, Zheng, Dongyu, Cheng, Ying, Yu, Rentao, Han, Gaige, Schmidt, Martina, Han, Li
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255654/
https://ncbi.nlm.nih.gov/pubmed/22083709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05830-11
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