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Distinct Strategies Are Required to Suppress Antigen-specific Responses to Genetically Modified Keratinocytes and Fibroblasts

Keratinocytes and fibroblasts are potential targets of gene/cell therapy for genodermatoses. Immune elimination of genetically modified cells, however, presents a major impediment to effective therapy. Using ex vivo approaches to gene transfer, we have previously shown that expression of an antigen...

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Bibliografiske detaljer
Main Authors: Ghazizadeh, Soosan, Huang, Li T, Zhang, Weibing
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255584/
https://ncbi.nlm.nih.gov/pubmed/21988876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.205
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