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2A Peptide-based, Lentivirus-mediated Anti-death Receptor 5 Chimeric Antibody Expression Prevents Tumor Growth in Nude Mice

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), a member of the TNF superfamily, induces tumor cell death via death receptors on target cells, without adverse effects on most normal cells. Its receptors are therefore an attractive target for antibody-mediated tumor therapy. He...

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Bibliografski detalji
Glavni autori: Li, Meng, Wu, Yaomin, Qiu, Yuhe, Yao, Zhenyu, Liu, Shilian, Liu, Yanxin, Shi, Juan, Zheng, Dexian
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255573/
https://ncbi.nlm.nih.gov/pubmed/21934654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.197
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