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Differential glycosylation of α-dystroglycan and proteins other than α-dystroglycan by like-glycosyltransferase
Genetic defects in like-glycosyltransferase (LARGE) cause congenital muscular dystrophy with central nervous system manifestations. The underlying molecular pathomechanism is the hypoglycosylation of α-dystroglycan (α-DG), which is evidenced by diminished immunoreactivity to IIH6C4 and VIA4-1, antib...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3255506/ https://ncbi.nlm.nih.gov/pubmed/21930648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwr131 |
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