The Carbohydrate-Binding Site in Galectin-3 Is Preorganized To Recognize a Sugarlike Framework of Oxygens: Ultra-High-Resolution Structures and Water Dynamics

[Image: see text] The recognition of carbohydrates by proteins is a fundamental aspect of communication within and between living cells. Understanding the molecular basis of carbohydrate–protein interactions is a prerequisite for the rational design of synthetic ligands. Here we report the high- to...

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Main Authors: Saraboji, Kadhirvel, Håkansson, Maria, Genheden, Samuel, Diehl, Carl, Qvist, Johan, Weininger, Ulrich, Nilsson, Ulf J., Leffler, Hakon, Ryde, Ulf, Akke, Mikael, Logan, Derek T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2011
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255464/
https://ncbi.nlm.nih.gov/pubmed/22111949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201459p
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