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Synthesis and antimalarial evaluation of some 4-quinazolinone derivatives based on febrifugine

A series of 2-substituted and 2,3-substituted quinazolin -4(3H)-one derivatives were designed and synthesized based on the structure of febrifugine. The structures of the new compounds were confirmed by spectral analysis. The in vivo biological activity test results indicated that those compounds ex...

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Main Authors: Sen, Debanjan, Banerjee, Anirban, Ghosh, Ashoke Kumar, Chatterjee, Tapan Kumar
Formato: Artigo
Idioma:Inglês
Publicado: Medknow Publications & Media Pvt Ltd 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255402/
https://ncbi.nlm.nih.gov/pubmed/22247880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0110-5558.76439
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