The identification of irreversible rituximab-resistant lymphoma caused by CD20 gene mutations

C-terminal mutations of CD20 constitute part of the mechanisms that resist rituximab therapy. Most CD20 having a C-terminal mutation was not recognized by L26 antibody. As the exact epitope of L26 has not been determined, expression and localization of mutated CD20 have not been completely elucidate...

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Detalhes bibliográficos
Main Authors: Mishima, Y, Terui, Y, Takeuchi, K, Matsumoto-Mishima, Y, Matsusaka, S, Utsubo-Kuniyoshi, R, Hatake, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255244/
https://ncbi.nlm.nih.gov/pubmed/22829136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2011.11
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