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Production of De Novo Cardiomyocytes: Human Pluripotent Stem Cell Differentiation and Direct Reprogramming

Cardiovascular disease is a leading cause of death worldwide. The limited capability of heart tissue to regenerate has prompted method developments for creating de novo cardiomyocytes, both in vitro and in vivo. Beyond uses in cell replacement therapy, patient-specific cardiomyocytes may find applic...

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Detalhes bibliográficos
Main Authors: Burridge, Paul W., Keller, Gordon, Gold, Joseph D., Wu, Joseph C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255078/
https://ncbi.nlm.nih.gov/pubmed/22226352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.12.013
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