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DNA Display Selection of Peptide Ligands for a Full-Length Human G Protein-Coupled Receptor on CHO-K1 Cells

The G protein-coupled receptors (GPCRs), which form the largest group of transmembrane proteins involved in signal transduction, are major targets of currently available drugs. Thus, the search for cognate and surrogate peptide ligands for GPCRs is of both basic and therapeutic interest. Here we des...

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Detalhes bibliográficos
Main Authors: Doi, Nobuhide, Yamakawa, Natsuko, Matsumoto, Hideaki, Yamamoto, Yasutsugu, Nagano, Tetsuya, Matsumura, Nobutaka, Horisawa, Kenichi, Yanagawa, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254644/
https://ncbi.nlm.nih.gov/pubmed/22253889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030084
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