Association analysis of PARP1 polymorphisms with Parkinson’s disease

Alpha-synuclein accumulation in intracellular inclusions, oxidative stress and microglia-mediated inflammation in the substantia nigra are crucial events in the pathogenesis of Parkinson’s disease (PD). Poly (ADP-ribose) polymerase-1 (PARP1), a DNA-binding enzyme and transcriptional regulator, plays...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Brighina, Laura, Riva, Chiara, Bertola, Francesca, Fermi, Silvia, Saracchi, Enrico, Piolti, Roberto, Goldwurm, Stefano, Pezzoli, Gianni, Ferrarese, Carlo
Format: Artigo
Langue:Inglês
Publié: Elsevier Science 2011
Sujets:
Short Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254239/
https://ncbi.nlm.nih.gov/pubmed/21767974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2011.06.022
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