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Microtubule destabilization is shared by genetic and idiopathic Parkinson's disease patient fibroblasts.

Data from both toxin-based and gene-based models suggest that dysfunction of the microtubule system contributes to the pathogenesis of Parkinson's disease, even if, at present, no evidence of alterations of microtubules in vivo or in patients is available. Here we analyze cytoskeleton organization i...

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Bibliografiske detaljer
Principais autores: Daniele Cartelli, Stefano Goldwurm, Francesca Casagrande, Gianni Pezzoli, Graziella Cappelletti
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2012-01-01
Serier:PLoS ONE
Online adgang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0037467&type=printable
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