Rapid measurement of antituberculosis drug activity in vitro and in macrophages using bioluminescence

OBJECTIVES: Tuberculosis drug development is hampered by the slow growth of Mycobacterium tuberculosis. Bioluminescence, light produced by an enzymatic reaction, constitutes a rapid and highly sensitive measurement of cell metabolic function that can be used as an indirect marker of cell viability i...

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Bibliographic Details
Main Authors: Andreu, Nuria, Fletcher, Taryn, Krishnan, Nitya, Wiles, Siouxsie, Robertson, Brian D.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254196/
https://ncbi.nlm.nih.gov/pubmed/22101217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkr472
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