Nitrosatable Drug Exposure During Early Pregnancy and Neural Tube Defects in Offspring: National Birth Defects Prevention Study

Nitrosatable drugs, such as secondary or tertiary amines and amides, form N-nitroso compounds in the presence of nitrite. Various N-nitroso compounds have been associated with neural tube defects in animal models. Using data from the National Birth Defects Prevention Study, the authors examined nitr...

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Hauptverfasser: Brender, Jean D., Werler, Martha M., Kelley, Katherine E., Vuong, Ann M., Shinde, Mayura U., Zheng, Qi, Huber, John C., Sharkey, Joseph R., Griesenbeck, John S., Romitti, Paul A., Langlois, Peter H., Suarez, Lucina, Canfield, Mark A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254159/
https://ncbi.nlm.nih.gov/pubmed/22047825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwr254
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