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Transient transfection of serum-free suspension HEK 293 cell culture for efficient production of human rFVIII
BACKGROUND: Hemophilia A is a bleeding disorder caused by deficiency in coagulation factor VIII. Recombinant factor VIII (rFVIII) is an alternative to plasma-derived FVIII for the treatment of hemophilia A. However, commercial manufacturing of rFVIII products is inefficient and costly and is associa...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3254136/ https://ncbi.nlm.nih.gov/pubmed/22115125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-114 |
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