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The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas

BACKGROUND: The PI3K/Akt pathway is involved in cellular survival pathways by inhibiting apoptotic processes and stimulating cell growth and proliferation. Its negative prognostic value has been proven in many types of cancer. In soft tissue sarcomas, the expression profiles of the PI3K/Akt pathway...

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Detalhes bibliográficos
Main Authors: Valkov, Andrej, Kilvaer, Thomas K, Sorbye, Sveinung W, Donnem, Tom, Smeland, Eivind, Bremnes, Roy M, Busund, Lill-Tove
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254077/
https://ncbi.nlm.nih.gov/pubmed/22107784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-200
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