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The GABA(A) Receptor Agonist THIP Ameliorates Specific Behavioral Deficits in the Mouse Model of Fragile X Syndrome

Hyperactivity, hypersensitivity to auditory stimuli, and exaggerated fear are common behavioral abnormalities observed in individuals with fragile X syndrome (FXS), a neurodevelopmental disorder that is the most common genetic cause of autism. Evidence from studies of the Fmr1 knockout (KO) mouse mo...

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Библиографические подробности
Главные авторы: Olmos-Serrano, Jose Luis, Corbin, Joshua G., Burns, Mark P.
Формат: Artigo
Язык:Inglês
Опубликовано: S. Karger AG 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254038/
https://ncbi.nlm.nih.gov/pubmed/22067669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000332884
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