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AMP-activated Protein Kinase Regulates E3 Ligases in Rodent Heart
RATIONALE: The degradation of proteins by the ubiquitin proteasome system (UPS) is required for the maintenance of cellular homeostasis in the heart. An important regulator of metabolic homeostasis is AMP-activated protein kinase (AMPK). AMPK activation inhibits protein synthesis and activates autop...
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Hauptverfasser: | , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2011
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3254015/ https://ncbi.nlm.nih.gov/pubmed/21921267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.252742 |
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