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AMP-Activated Protein Kinase Regulates Neuronal Polarization by Interfering with PI 3-Kinase Localization

Axon-dendrite polarization is crucial for neural network wiring and information processing in the brain. Polarization begins with the transformation of a single neurite into an axon and its subsequent rapid extension, which requires coordination of cellular energy status to allow for transport of bu...

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Bibliographic Details
Main Authors: Amato, Stephen, Liu, Xiuxin, Zheng, Bin, Cantley, Lewis, Rakic, Pasko, Man, Heng-Ye
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325765/
https://ncbi.nlm.nih.gov/pubmed/21436401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1201678
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