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The DNA Replication Stress Hypothesis of Alzheimer's Disease
A well-recognized theory of Alzheimer's disease (AD) pathogenesis suggests ectopic cell cycle events to mediate neurodegeneration. Vulnerable neurons of the AD brain exhibit biomarkers of cell cycle progression and DNA replication suggesting a reentry into the cell cycle. Chromosome reduplicati...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
TheScientificWorldJOURNAL
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3254013/ https://ncbi.nlm.nih.gov/pubmed/22262948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/2011/625690 |
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