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Electron microscopy visualization of DNA-protein complexes formed by Ku and DNA ligase IV
The repair of DNA double-stranded breaks (DSBs) is essential for cell viability and genome stability. Aberrant repair of DSBs has been linked with cancer predisposition and aging. During the repair of DSBs by non-homologous end joining (NHEJ), DNA ends are brought together, processed and then joined...
Kaydedildi:
Asıl Yazarlar: | , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2011
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253911/ https://ncbi.nlm.nih.gov/pubmed/22088982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.10.023 |
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