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In Vivo Imaging of Ligand Receptor Binding with Gaussia Luciferase Complementation

Studies of ligand-receptor binding and development of receptor antagonists would benefit greatly from imaging techniques that translate directly from cell-based assays to living animals. We used Gaussia luciferase protein fragment complementation to quantify binding of chemokine CXCL12 to receptors...

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Hlavní autoři: Luker, Kathryn E., Mihalko, Laura Anne, Schmidt, Bradley T., Lewin, Sarah A., Ray, Paramita, Shcherbo, Dmitry, Chudakov, Dmitriy M., Luker, Gary D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253890/
https://ncbi.nlm.nih.gov/pubmed/22138753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2590
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