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Purification, crystallization and preliminary X-ray diffraction analysis of the IL-20–IL-20R1–IL-20R2 complex

Interleukin-20 (IL-20) is an IL-10-family cytokine that regulates innate and adaptive immunity in skin and other tissues. In addition to protecting the host from various external pathogens, dysregulated IL-20 signaling has been shown to contribute to the pathogenesis of human psoriasis. IL-20 signal...

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Detalhes bibliográficos
Main Authors: Logsdon, Naomi J., Allen, Christopher E., Rajashankar, Kanagalaghatta R., Walter, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253844/
https://ncbi.nlm.nih.gov/pubmed/22232181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111049529
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