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Generation of Long Insert Pairs Using a Cre-LoxP Inverse PCR Approach

Large insert mate pair reads have a major impact on the overall success of de novo assembly and the discovery of inherited and acquired structural variants. The positional information of mate pair reads generally improves genome assembly by resolving repeat elements and/or ordering contigs. Currentl...

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Detalles Bibliográficos
Main Authors: Peng, Ze, Zhao, Zhiying, Nath, Nandita, Froula, Jeff L., Clum, Alicia, Zhang, Tao, Cheng, Jan-fang, Copeland, Alex C., Pennacchio, Len A., Chen, Feng
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253782/
https://ncbi.nlm.nih.gov/pubmed/22253722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029437
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