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An Evaluation of Peptide-Bond Isosteres
Peptide-bond isosteres can enable a deep interrogation of the structure and function of a peptide or protein by amplifying or attenuating particular chemical properties. In this minireview, the electronic, structural, and conformational attributes of four such isosteres—thioamides, esters, alkenes,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253576/ https://ncbi.nlm.nih.gov/pubmed/21751326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201100272 |
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