TRC120038, a Novel Dual AT(1)/ET(A) Receptor Blocker for Control of Hypertension, Diabetic Nephropathy, and Cardiomyopathy in ob-ZSF1 Rats

In hypertensive subjects, angiotensin II and endothelin participate in a manner involving closely interwoven pathways in increasing blood pressure (BP) and inducing end organ damage. The primary objective of this study was to determine the effect of TRC120038, a novel dual AT(1)/ET(A) receptor block...

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Hauptverfasser: Mohanan, Anookh, Gupta, Ram, Dubey, Amita, Jagtap, Vikrant, Mandhare, Appaji, Gupta, Ramesh C., Chauthaiwale, Vijay, Dutt, Chaitanya
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE-Hindawi Access to Research 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253485/
https://ncbi.nlm.nih.gov/pubmed/22235363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/751513
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