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NEMO-LIKE KINASE INHIBITS OSTEOBLASTOGENESIS BY SUPPRESSING BONE MORPHOGENETIC PROTEIN AND WNT CANONICAL SIGNALING
The bone morphogenetic protein/Signaling mothers against decapentaplegic (BMP/Smad) and the WNT signaling pathways regulate the commitment of mesenchymal cells to the osteoblastic lineage. Nemo like kinase (Nlk) is an evolutionary conserved kinase that suppresses Smad transactivation and WNT canonic...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253257/ https://ncbi.nlm.nih.gov/pubmed/21928348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23365 |
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