Regulation of Hepatic Lipin-1 by Ethanol: Role of AMPK-SREBP-1 Signaling

Lipin-1 is a protein that exhibits dual functions as a phosphatidic acid phosphohydrolase (PAP) enzyme in the triglyceride synthesis pathways and a transcriptional co-regulator. Our previous studies have shown that ethanol causes fatty liver by activation of sterol regulatory element-binding protein...

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Главные авторы: Hu, Ming, Wang, Fengming, Li, Xin, Rogers, Christopher Q., Liang, Xiaomei, Finck, Brian N., Mitra, Mayurranjan S., Zhang, Ray, Mitchell, Dave A., You, Min
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253249/
https://ncbi.nlm.nih.gov/pubmed/21953514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24708
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