Rapid Generation of MicroRNA Sponges for MicroRNA Inhibition

MicroRNA (miRNA) sponges are transcripts with repeated miRNA antisense sequences that can sequester miRNAs from endogenous targets. MiRNA sponges are valuable tools for miRNA loss-of-function studies both in vitro and in vivo. We developed a fast and flexible method to generate miRNA sponges and tes...

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Bibliografiska uppgifter
Huvudupphovsmän: Kluiver, Joost, Gibcus, Johan H., Hettinga, Chris, Adema, Annelies, Richter, Mareike K. S., Halsema, Nancy, Slezak-Prochazka, Izabella, Ding, Ye, Kroesen, Bart-Jan, van den Berg, Anke
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253070/
https://ncbi.nlm.nih.gov/pubmed/22238599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029275
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