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The role of the histone H2A ubiquitinase Sce in Polycomb repression
Polycomb group (PcG) proteins exist in multiprotein complexes that modify chromatin to repress transcription. Drosophila PcG proteins Sex combs extra (Sce; dRing) and Posterior sex combs (Psc) are core subunits of PRC1-type complexes. The Sce:Psc module acts as an E3 ligase for monoubiquitylation of...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Company of Biologists
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253035/ https://ncbi.nlm.nih.gov/pubmed/22096074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.074450 |
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