Chromatin-modifying Complex Component Nurf55/p55 Associates with Histones H3 and H4 and Polycomb Repressive Complex 2 Subunit Su(z)12 through Partially Overlapping Binding Sites

Drosophila Nurf55 is a component of different chromatin-modifying complexes, including the PRC2 (Polycomb repressive complex 2). Based on the 1.75-Å crystal structure of Nurf55 bound to histone H4 helix 1, we analyzed interactions of Nurf55 (Nurf55 or p55 in fly and RbAp48/46 in human) with the N-te...

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Main Authors: Nowak, Agnieszka J., Alfieri, Claudio, Stirnimann, Christian U., Rybin, Vladimir, Baudin, Florence, Ly-Hartig, Nga, Lindner, Doris, Müller, Christoph W.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2011
主題:
DNA and Chromosomes
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123103/
https://ncbi.nlm.nih.gov/pubmed/21550984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.207407
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