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Double-stranded RNA-dependent protein kinase activation modulates endotoxin-induced diaphragm weakness
Diaphragm caspase-8 activation plays a key role in modulating sepsis-induced respiratory muscle dysfunction. It is also known that double-stranded RNA-dependent protein kinase (PKR) is a regulator of caspase-8 activation in neural tissue. We tested the hypothesis that the PKR pathway modulates sepsi...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253003/ https://ncbi.nlm.nih.gov/pubmed/21071594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01203.2009 |
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