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Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures

Here we present a meta-analysis of a large collection of static structures of a protein in the Protein Data Bank in order to extract the progression of structural events during protein function. We apply this strategy to the homodimeric hemoglobin HbI from Scapharca inaequivalvis. We derive a simple...

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Bibliographic Details
Main Authors: Ren, Zhong, Šrajer, Vukica, Knapp, James E., Royer, William E.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252913/
https://ncbi.nlm.nih.gov/pubmed/22171006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109213108
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