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Allosteric action in real time: Time-resolved crystallographic studies of a cooperative dimeric hemoglobin

Protein allostery provides mechanisms for regulation of biological function at the molecular level. We present here an investigation of global, ligand-induced allosteric transition in a protein by time-resolved x-ray diffraction. The study provides a view of structural changes in single crystals of...

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Detalhes bibliográficos
Main Authors: Knapp, James E., Pahl, Reinhard, Šrajer, Vukica, Royer, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472499/
https://ncbi.nlm.nih.gov/pubmed/16684887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509411103
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