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The PIDDosome, DNA-damage-induced apoptosis and beyond

P53-induced protein with a death domain (PIDD) was cloned as a death domain (DD)-containing protein whose expression is induced by p53. It was later described as the core of a molecular platform-activating caspase-2, named the PIDDosome. These first results pointed towards a role for PIDD in apoptos...

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Bibliografiske detaljer
Main Authors: Janssens, S, Tinel, A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252840/
https://ncbi.nlm.nih.gov/pubmed/22095286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.162
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