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Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice

Autophagy is an essential recycling pathway implicated in neurodegeneration either as a pro-survival or a pro-death mechanism. Its role after axonal injury is still uncertain. Axotomy of the optic nerve is a classical model of neurodegeneration. It induces retinal ganglion cell death, a process also...

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Detalhes bibliográficos
Main Authors: Rodríguez-Muela, N, Germain, F, Mariño, G, Fitze, P S, Boya, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252838/
https://ncbi.nlm.nih.gov/pubmed/21701497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.88
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