Cyclic AMP induces IPC leukemia cell apoptosis via CRE-and CDK-dependent Bim transcription

The IPC-81 cell line is derived from the transplantable BNML model of acute myelogenic leukemia (AML), known to be a reliable predictor of the clinical efficiency of antileukemic agents, like the first-line AML anthracycline drug daunorubicin (DNR). We show here that cAMP acted synergistically with...

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Bibliografski detalji
Glavni autori: Huseby, S, Gausdal, G, Keen, T J, Kjærland, E, Krakstad, C, Myhren, L, Brønstad, K, Kunick, C, Schwede, F, Genieser, H-G, Kleppe, R, Døskeland, S O
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
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Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252733/
https://ncbi.nlm.nih.gov/pubmed/22158476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.124
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