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Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence

Cellular senescence acts as a potent barrier for tumour initiation and progression. Previous studies showed that the PML tumour suppressor promotes senescence, although the precise mechanisms remain to be elucidated. Combining gene expression profiling with chromatin-binding analyses and promoter re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Martin, Nadine, Benhamed, Moussa, Nacerddine, Karim, Demarque, Maud D, van Lohuizen, Maarten, Dejean, Anne, Bischof, Oliver
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252579/
https://ncbi.nlm.nih.gov/pubmed/22002537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.370
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